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  1. J Am Acad Dermatol 1992. Thus the effectiveness and tretinoin safety of renova (tretinoin cream).02 in these populations are not known at this time. Tretinoin emollient cream: a new therapy for photodamaged skin.

  2. Carcinogenesis, Mutagenesis, Impairment to Fertility: In a tretinoin cream 0.1 91-week dermal study in which CD-1 mice were administered.017 and.035 formulations of Tretinoin, cutaneous squamous cell carcinomas and papillomas in the treatment area were observed in some female mice. This effect has been confirmed in a later study in pigmented mice, and dark pigmentation did not overcome the enhancement of photocarcinogenesis.05 Tretinoin. Apply tretinoin once daily before bedtime, or as directed by your physician.

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